This can take the shape of destructive behaviors, confusing or irrational patterns of speech, or sudden outbursts of anger and violence that can last for days after last using methamphetamine. Tweaking can refer to the nervous, repeated physical motions that meth users engage in or to the unpredictable mood swings and violent outbursts that accompany meth usage. “Tweaking” is a slang term for the compulsive, disorganized behavior that methamphetamine users exhibit, particularly after large doses or long periods of repeated dosing.
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